U.C. Irvine Publications

46. Overstreet, C.M., Levin, A.M., Kong, C., Coroneus, J.G., Weiss, G.A. (2008). Harnessing a self-made phage library (SMPL). Submitted.

45. Diaz, J.E., Lin, C.-S., Kunishiro, K., Feld, B.K., Avrantinis, S.K., Bronson, J., Greaves, J., Saven, J.G., Weiss, G.A. (2008). Computational design, selections, and screens for an engineered terpene synthase. Submitted.

44. Lamboy, J.A., Arter, J.A., Knopp, K.A., Der, D., Overstreet, C.M., Palermo, E., Urakami, H., Yu, T.-B., Tezgel, O., Tew, G.N., Guan, Z., Kuroda, K., Weiss, G.A.* (2009). Phage wrapping with cationic polymers eliminates non-specific binding between M13 phage and high pI target proteins. J. Amer. Chem. Soc. In press.

43. Lamboy, J.A., Tam, P.Y., Lee, L.S., Jackson, P.J., Avrantinis, S.K., Lee, H.J., Corn, R.M., Weiss, G.A. (2008). Chemical and genetic wrappers for improved phage and RNA display. ChemBioChem. In press.

42. Majumdar, S.*, Hajduczki, A.*, Mendez, A.S., Weiss, G.A. (2008). Phage display of functional, full-length human and viral membrane proteins. Bioorg. Med. Chem. Lett. *Joint First Authors. In press.

41. Yang, L.-M., Diaz, J.J., McIntire, T., Weiss, G.A., Penner, R.M. (2008). Direct electrical transduction of antibody binding to a covalent virus layer using electrochemical impedance. Anal. Chem. 80: 5695-5705. Accelerated article. PDF

40. Coroneus, J.G., Goldsmith, B., Lamboy, J.A., Kane, A.A., Collins, P.G.*, Weiss, G.A.* (2008). Mechanism-guided improvements to the single molecule oxidation carbon nanotube sidewalls. ChemPhysChem. 9: 1053-1056. PDF

39. Weiss, G.A.*, Penner, R.M.* (2008). The promise of phage display: customized affinity and specificity. Anal. Chem. 80: 933-943. PDF

38. Goldsmith, B., Coroneus, J.G., Weiss, G.A., Collins, P.G.* (2008). Scaffolding carbon nanotubes into single-molecules circuitry. J. Mater. Res. 1018: 1018-EE08-07. PDF

37. Goldsmith, B.R., Coroneus, J.G., Kane, A.A., Weiss, G.A., Collins, P.G.* (2008). Monitoring single molecule reactivity on a carbon nanotube. Nano Lett. 8: 189-194. PDF

36. Yang, L.-M.C., Diaz, J.E., McIntire, T.M., Weiss, G.A.*, Penner, R.M.* (2008). Covalent virus layers for mass-based detection. Anal. Chem. 80: 933-943. PDF

35. Diaz, J.E., Yang, L.-M.C., Lamboy, J.A., Penner, R.M.*, Weiss, G.A.* (2008). Synthesis of a virus electrode for measurement of prostate specific membrane antigen. Methods Mol. Biol. 504: 255-274.

34. Weiss, G.A. (2007). Exploring the Milky Way of molecular diversity: Combinatorial chemistry and molecular diversity. Curr. Opin. Chem. Biol. 11: 241-243. PDF

33. Levin, A.M.,* Murase, K.,* Jackson, P.J., Flinspach, M.L., Poulos, T.L., Weiss, G.A. (2007). Double barrel shotgun scanning of the caveolin-1 scaffolding domain. ACS Chem. Biol.  2: 493-500. *Joint First Authors. Featured on the journal cover. PDF

32. Goldsmith, B., Coroneus, J.G., Khalap, V.R., Kane, A.A., Weiss, G.A., Collins, P.G.* (2007). Conductance-controlled point functionalization of single-walled carbon nanotubes. Science. 315: 77-81. PDF
Featured in Chemistry & Engineering News. Link Erratum in Science (2007) 318: 1866. PDF

31. Yang, L.-M.C., Tam, P.Y., Murray, B.J., McIntire, T.M., Overstreet, C.M., Weiss, G.A.,* Penner, R.M.* (2006). Virus electrodes for universal biodetection. Anal. Chem. 78: 3265-3270. *Corresponding authors. Featured on the journal cover. PDF

30. Levin, A.M., Coroneus, J.G., Cocco, M.J., Weiss, G.A. (2006). Exploring the interaction between the protein kinase A catalytic subunit and Caveolin-1 scaffolding domain with shotgun scanning, oligomer complementation, NMR, and docking. Prot. Science. 15: 478-486. PDF

29. Feld, B.K., Weiss, G.A. (2006). Improved syntheses of P1-allyl-P2-substituted diphosphates. Bioorg. Med. Chem. Lett. 16: 1665-1667. PDF

28. Morrison, K.L., Weiss, G.A. (2006). The origins of chemical biology. Nat. Chem. Biol. 2: 3-6. PDF

27. Levin, A.M., Weiss, G.A. (2006). Optimizing the affinity and specificity of proteins with molecular display. Mol. BioSystems. 2: 49-57. PDF

26. Olszewski, A., Weiss, G.A. (2005). Library versus library recognition and inhibition of the HIV-1 Nef allelome. J. Am. Chem. Soc. 127: 12178-12179. PDF

25. Wassman, C.D.,* Tam, P.Y.,* Lathrop, R.H., Weiss, G.A. (2004). Predicting oligonucleotide-directed mutagenesis failures in protein engineering. Nucleic Acids Res. 32: 6407-6413. *Joint First Authors. Cross hybridization score calculator. PDF

24. Olszewski, A., Sato, K., Aron, Z.D., Cohen, F., Harris, A., McDougall, B.R, Robinson, Jr., W.E., Overman, L.E., Weiss, G.A.(2004). Guanidine alkaloid analogs as inhibitors of HIV-1 Nef interactions with p53, actin and p56lck. Proc. Natl. Acad. Sci. USA. 101: 14079-14084. PDF

23. Simon, M.D., Sato, K., Weiss, G.A., Shokat, K.M. (2004). A phage display selection of engrailed homeodomain mutants and the importance of residue Q50. Nucleic Acids Res. 32: 3623-3631. PDF

22. Sato, K., Simon, M.D., Levin, A.M., Shokat, K.M., Weiss, G.A. (2004). Dissecting the engrailed homeodomain-DNA interaction by phage-displayed shotgun scanning. Chem. Biol. 11:1017-1023. PDF
Cover by Aron Levin. PDF     Preview by Scot Wolfe (2004). Chem. Biol. 11: 889-891. PDF

21. Diaz, J.E., Howard, B.E., Neubauer, M.S., Olszewski, A., Weiss, G.A. (2003). Exploring biochemistry and cellular biology with protein libraries. Curr. Issues Mol. Biol. 5: 129-146. PDF

20. Weiss, G.A., Chamberlin, A.R. (2003). Bridging the synthetic and biopolymer worlds with peptide-drug conjugates. Chem. Biol. 10: 201-202. PDF

19. Murase, K., Morrison, K.L., Tam, P.Y., Stafford, R.L., Jurnak, F., Weiss, G.A. (2003). EF-Tu binding peptides identified, dissected and affinity optimized by phage display. Chem. Biol. 10: 161-168. PDF

18. Sidhu, S.S.*, Feld, B.K., Weiss, G.A.* (2007). M13 bacteriophage coat proteins engineered for improved phage display. Methods Mol. Biol. 352: 205-219.

17. Avrantinis, S.K., Weiss, G.A. (2002). Dissecting protein functional epitopes with phage display. Phage Display in Biotechnology and Drug Discovery, Taylor & Francis Group, LLC (Sidhu, S.S., ed.). 441-460.

16. Avrantinis, S.K., Stafford, R., Tian, X., Weiss, G.A. (2002). Dissecting the streptavidin-biotin interaction by phage-displayed shotgun scanning. ChemBioChem. 3: 1229-1234. PDF

15. Weiss, G.A. (2001). Leading the way: training future chemical biologists. Chem. Innovation. 31: 3-4. PDF

14. Morrison, K.L., Weiss, G.A. (2001). Combinatorial alanine scanning. Curr. Opin. Chem. Biol. 5: 302-307.  PDF

Genentech Publications

13. Sidhu, S.S., Weiss, G.A. (2004). Chapter 2. Constructing phage display libraries by oligonucleotide-directed mutagenesis. Phage Display: A Practical Approach, Oxford University Press (Lowman, H.L. & Clackson, T., eds.), pp. 27-41.  

12. Weiss, G.A., Roth, T.A., Baldi, P.F., Sidhu, S.S. (2003). Comprehensive mutagenesis of the C-terminal domain of the gene-3 minor coat protein: the requirements for assembly into the bacteriophage particle. J. Mol. Biol. 332: 777-782. PDF

11. Roth, T.A., Weiss, G.A., Eigenbrot, C., Sidhu, S.S. (2002). A minimized M13 coat protein defines the minimum requirements for assembly into the bacteriophage particle. J. Mol. Biol. 322: 357-367. PDF

10. Sidhu, S.S., Weiss, G.A. (2001). Engineered micro-organisms as sources of new drugs. Anticancer Drug Development, Academic Press (Baguley, B. & Kerr, D., eds.), 237-248. 

9. Weiss, G.A., Lowman, H.B. (2000). Anticalins versus antibodies: made-to-order binding proteins for small molecules. Chem. Biol.7: R177-R184. PDF

8. Weiss, G.A., Watanabe, C.K., Goddard, A., Zhang, A., Sidhu, S.S. (2000). Rapid mapping of functional protein epitopes by combinatorial alanine-scanning. Proc. Natl. Acad. Sci. USA. 97: 8950-8954. PDF

7. Weiss, G.A., Sidhu, S.S. (2000). Design and evolution of artificial M13 coat proteins. J. Mol. Biol. 300: 213-219. PDF 

6. Weiss, G.A., Sidhu, S.S., Wells, J.A. (2000). Mutational analysis of the major coat protein of M13 identifies residues that control protein display. Protein Sci. 9: 647-654.  PDF

5. Sidhu, S.S., Weiss, G.A., Wells, J.A. (2000). High copy display of large proteins on M13 phage for functional selections. J. Mol. Biol. 296: 487-495.  PDF

Harvard and U.C. Berkeley Publications

4. Evensen, E., Joseph-McCarthy, D., Weiss, G.A., Schreiber, S.L., Karplus, M. (2007). Ligand design by a combinatorial approach based on modeling and experiment: application to HLA-DR4. J. Comput. Aided Mol. Des. 21: 395-418. PDF

3. Weiss, G.A., Valentekovich, R.J., Collins, E.J., Garboczi, D.N., Schreiber, S.L., Wiley, D.C. (1996). Covalent HLA-B27/peptide complex induced by specific recognition of an aziridine mimic of arginine. Proc. Natl. Acad. Sci. USA 93: 10945-10948. PDF

2. Weiss, G.A., Collins, E.J., Garboczi, D.N., Wiley, D.C., Schreiber, S.L. (1995). A tricyclic ring system replaces the variable regions of peptides presented by three alleles of human MHC class I molecules. Chem. Biol. 2: 401-407.  PDF

1. Karo, A.M., Deboni, T.M., Hardy, J.R., Weiss, G.A. (1990). Shock dynamics in the subnanometer femtosecond domain. Int. J. Quant. Chem. S24: 277-289. PDF